Stem cell technologies in human health: Boon or bane?

Author(s): Madhavi Tripathi, Sangeeta Singh

A flow chart showing how the Induced Pluripotent Stem Cells (iPSCs) can be formed from normal
fibroblast cells using different reprogramming factors viz. Nanog, Klf4, Sox2, c-Myc and Oct4. To be
noted that the iPSCs bear similar abilities as human embryonic stem cells i.e. capable to differentiate in any
type of cell present inside the individual except placental cells and have potential to treat several human
diseases like acute and chronic leukemias, myeloproliferative and lymphoproliferative disorders, inherited
diseases, malignancies, etc. by modelling them. Several other kinds of cells can be formed during the
process that can further be used for transplantation inside human body wherever required.

The stem cells of an organism only possess extraordinary capacity to change into different cell types during the early life and growth of an organism. When these stem cells divide into different new cells, these either remain as stem cells or develop to become other cells with specialized function. For this reason, stem Continue reading

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Development of a Reproducible Rating System for Sun Protective Clothing That Incorporates Body Surface Coverage

Author(s):Simone L. Harrison, Nathan Downs

Sunlight is a known skin carcinogen. Skin cancer is the most common form of cancer in humans, and typically affects sun-exposed parts of the body. Sunny Australia and New Zealand have the highest incidence of skin cancer globally. Clothing provides a protective barrier that reduces the amount of ultraviolet radiation (UVR) reaching the skin. Australia pioneered the development of a relative ranking of the sun-protective capabilities of clothing based on the transmission of UVR through fabric. Standardized Ultraviolet Protection Factor (UPF) measurement procedures Continue reading

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Connection between the Linoleic Acid and Psychopathology: A Symmetry-Breaking Phenomenon in the Brain?

Author(s): Massimo Cocchi, Chiara Minuto, Lucio Tonello, Jack A. Tuszynski


Schematic of the structural differences between saturated and unsaturated fatty acids.
Schematic of the structural differences between saturated
and unsaturated fatty acids.

In this paper we discuss the role of the fatty acid composition of brain cells and in platelets in the emergence of psychiatric disorders such as major depression and the bipolar disorder. We argue that the linoleic acid concentration plays the role of a control parameter and there is a critical value of the linoleic acid concentration that determines a transition from healthy mental state to a pathological state. We draw an analogy with symmetry breaking in physical systems where at a bifurcation point on the phase diagram, infinitesimal perturbations to the state of the system result in a transition to a new global attractor state. Continue reading

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Effect of Skin Pigmentation on Near Infrared Spectroscopy

Author(s): Luke Couch, Mellisa Roskosky, Brett A. Freedman, Michael S. Shuler

The purpose of this study was to determine the effects of skin pigmentation regarding Near Infrared Spectroscopy (NIRS) tissue oxygen saturation values (StO2). The study examined NIRS values in individuals with varying skin pigmentation on the anterior compartment of the lower leg and volar forearm to determine if correlation exists among three NIRS devices, the EQUANOX, Casmed, and INVOS. Skin pigmentation was measured on the anterior lower leg (AL) and volar forearm Continue reading

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Serum Antibody Titers of Measles and Rubella among Japanese Children

Author(s): Yuichirou Tsuji, Chitose Karasawa

Background: The rubella outbreak in Japan has not yet been eliminated. In particular, an outbreak of congenital rubella syndrome has recently become a public health problem in Japan. The World Health Organization has set an elimination target of 2015 for measles in Japan. However, an outbreak of measles occurred in Japan between 2007 and 2008. Starting in April 2006, the measles and rubella vaccines were administered twice, once when a child reached 1 year old and once when the child Continue reading

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Theory of a Mach Effect Thruster II

Author(s): Heidi Fearn1, Nolan van Rossum, Keith Wanser, James F. Woodward

According to Einstein, General Relativity contains the essence of Mach’s ideas. Mach’s principle can be summarized by stating that the inertia of a body is determined by the rest of the mass-energy content of the universe. Inertia here arises from mass-energy there. The latter, was a statement made by John Wheeler in his 1995 book, Gravitation and Inertia, coauthored by Ciufolini. Einstein believed that to be fully Machian, gravity would need a radiative component, an action-at-a-distance character, so that gravitational influences on a body from far away could be felt immediately. Continue reading

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Generalization of the Thermal Dose of Hyperthermia in Oncology

Author(s): Gyula Vincze, Oliver Szasz, Andras Szasz

Hyperthermia has been a modality to treat cancer for thousands of years. During this time, intensive efforts are concentrated on determining the dose of the proper treatment, but the dominantly in vitro induced cellular death does not provide enough confidence for the clinical dosing. The cell-death by heat-monotherapy applications in laboratory experiments is difficult to apply in the complementary therapies in clinical applications. The newly developed nanotechnologies offer Continue reading

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Aerodynamic Brake for Formula Cars

Author(s): Roberto Capata, Leone Martellucci

In the last years, in formula racing cars championships, the aerodynamic had reached an ever more important stance as a performance parameter. In the last four seasons, Red Bull Racing Technical Officer had designed their Formula 1 car with the specific aim to generate the optimal downforce, in relation to the car instantaneous setup. However, this extreme research of higher downforce brings some negative effects when a car is within the wake of another car; indeed, it is well known that under these condition the aerodynamic is disturbed, and it makes difficult to Continue reading

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The Theory of Everything as the Reversibility Theory

Author(s): Ding-Yu Chung

In the posited reversibility theory, 1) all physical laws and phenomena are permanently reversible, 2) all physical laws are derived from the reversible M-theory (extension of string theory) in the reversible multiverse, and 3) temporary irreversible entropy increase is allowed through reversibility breaking, symmetry breaking, and low entropy beginning. Dealing with all physical laws and phenomena, the reversibility theory is the theory of everything, including thermodynamic, cosmology, the composition (baryonic matter, dark matter, and dark energy) in the universe, the periodic table of all elementary particles, the galaxy evolution, superconductivity, and black hole. In the reversible M-theory, space-time dimension number oscillates between 11D (space-time dimension) and 10D and between 10D and 4D. The reversible M-theory includes 11D membrane Continue reading

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Review: Can Toxic Substances Initiate Psychotic Behavior? Part I. Antimalarial Drugs

Author(s): Ilia Brondz


Blue zone is chloroquine sensitive malaria, red zone is chloroquine resistant malaria, and black zone is multi-resistant malaria.
Blue zone is chloroquine sensitive malaria, red zone is chloroquine resistant malaria, and black zone is multi-resistant malaria.

During and after every military conflict or war, there appears to be rapports about military crimes which were done by military and civil personal of conflicting sides. The basis of these offences is different; however the common to these is psychological and psychical background. The psychological background is an indoctrination of troopers that all what they are doing is right, well for country, nation or defends religion, or ideology. The life and property of enemy (opponent) are Continue reading

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