Stem Cells: Daddy or Chips? —An Up-to-Date Review on Ground-Breaking Discoveries in Stem Cell Research, with Special Attention to iPSC Applications in Osteoarthritis

Author(s): Pierre Luc Pace, Renald Blundel

ABSTRACT
“Stem Cells is what stem cells does”
not Forrest Gump

SCF/SCFr mediated chemicalpathway inducing non-specific HSC proliferation
SCF/SCFr mediated chemicalpathway inducing non-specific HSC proliferation

In the present day Stem Cells are increasingly becoming popularized as the potential “ultimate” cure for the most challenging maladies… the “Daddy of medical intervention”. Forefront SC research on human induced pluripotent stem cells (iPSCs) and other sub-disciplines, is quickly revolutionizing healthcare towards “Regenerative Medicine”, as beautifully exemplified by the use of iPSCs in treating and possibly curing osteoarthritis, discussed at the end of this publication. This review documents and reflects on the most topical discoveries in SC research, and the challenges researchers in this field nowadays face. Major Findings: 1) In 2006 Yamanaka et al. generated the first iPSCs from mouse fibroblasts, using retroviral transmission of c-Myc, Oct3/4, Klf4 and SOX2 transcription factors. Continue reading

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Illegal Logging and Related Trade: Who Combat It as Legal Subjects?

Author(s): Jing Qian , Bin Xu , Hongqiang Yang, Ying Nie

ABSTRACT
Issue on illegal logging and related trade is a hot topic for the international community. It has brought the negative effects to the sustainable development on global society, economy and ecology, which is also one of the main objectives of international cooperation to combat with. At present, subjects of international law play a decisive role in combating illegal logging and related trade. The subjects of international law generally refer to states, intergovernmental organizations (IGOs) and part of non-governmental Continue reading

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The Financial and Economic Crisis, Its Impacts on the Shipping Industry, Lessons to Learn: The Container-Ships Market Analysis

Author(s): Bomboma Kalgora, Tshibuyi Mutinga Christian

ABSTRACT

. Global newbuilding order cover (figure caption). Source: Shipping Market Review, April 2013. Clarksons, Danish Ship Finance. Page 10, figure SB.1.
. Global newbuilding order cover (figure caption). Source: Shipping Market Review,
April 2013. Clarksons, Danish Ship Finance. Page 10, figure SB.1.

The container shipping, the important beneficiary and the major element of globalization, has remained a way of moving goods all over the world at an ever-increasing pace since not long ago. With China becoming the world’s factory, the industry has known a sustained and rapid growth from year to year. Continue reading

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The Value of Music in Children’s Enlightenment Education

Author(s): Jue Zhou

ABSTRACT
A large number of theories and experiments have shown that music plays positive effect on children’s growth. Children who have received music education often show outstanding creativity and imagination in their school lives, compared with their peers who have not get any musical training. Just as famous educator Dr. Hans Gunther Bastian has once proposed: “music makes people smart”. Learning music can not only improve children’s intelligence and morality which contributes to the development of their personality, but also can improve their aesthetic ability. Cultivate music to children is an essential progress to promote all-ground education. Continue reading

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On a Simpler, Much More General and Truly Marvellous Proof of Fermat’s Last Theorem (I)

Author(s): Golden Gadzirayi Nyambuya

ABSTRACT
English mathematics Professor, Sir Andrew John Wiles of the University of Cambridge finally and conclusively proved in 1995 Fermat’s Last Theorem which had for 358 years notoriously resisted all gallant and spirited efforts to prove it even by three of the greatest mathematicians of all time—such as Euler, Laplace and Gauss. Sir Professor ​​Andrew Wiles’s proof employed very advanced mathematical tools and methods that were not at all available in the known World during Fermat’s days. Continue reading

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Diabetes, Obesity and the Nutrition Transition in the Mercosur

Author(s) :Tatiane Andreazza Lucchese, Amanda Maia Breis, Karine Rucker, Vagner Rosa Bizarro, Lis Marina Mesquita Araújo, Alessandre Gomes, Mikele Torino Paletti, Ana Luísa Conceição de Jesus, Marcella Garcez Duarte, Denise Rosso Tenório Wanderley Rocha, Alberto Krayyem Arbex

ABSTRACT
Diabetes and obesity are major health hazards in Latin America nowadays. Their prevalence has steadily increased since the eighties. Today, more than 50% of the population are overweight, 15% has obesity and 6% to 15% has diabetes. The nutrition transition is a long-term process that brings chronic metabolic diseases as an undesired consequence, whilst ultra processed foods become increasingly part of daily food choices. These changes bring impacts in all fields of daily life, especially in the economic Continue reading

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The Effective Temperature and the Absolute Magnitude of the Stars

Author(s): Angel Fierros Palacios

ABSTRACT
The theoretical framework developed by A.S. Eddington for the study of the inner structure and stability of the stars has been modified by the author and used in this work to show that knowing the effective temperature and the absolute magnitude, the basic parameters of any gaseous star can be calculated. On the other hand, a possible theoretical explanation of the Hertzsprung-Russel Diagram is presented. Continue reading

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Health, Physical Activity and the Rio de Janeiro 2016 Olympic Games: Legacy or Fallacy?

Author(s): Vagner Rosa Bizarro, Tatiane Andreazza Lucchese, Amanda Maia Breis, Karine Rucker, Minelli Salles Alves Fernandes, Mikele Torino Paletti, Ana Luísa Conceição de Jesus, Raphael Calafange Marques Pereira, Denise Rosso Tenório Wanderley Rocha, Alberto Krayyem Arbex

ABSTRACT
It is generally expected that the Rio de Janeiro 2016 Olympic and Paralympic Games will bring health and social benefits to their host city and to Brazil. This assumption comes from “common sense”, as a logical conclusion arising from the fact that host cities “inspire” and stimulate lifestyle changes. Benefits are also expected on tourism, self-image, architecture and the economy of the country as a whole. Continue reading

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Enhancement of Toxic Gas Detecting Ability of Film Type Colorimetric Sensor

Author(s): Sung Yeol Kim, Seung Kyun Yoon , Jungho Ahn, Dong June Chung

ABSTRACT

Impregnation coating method
Impregnation coating method

In this study, we tried to develop the in situ coating methods of hydrophilic polymer solution containing water soluble dye on nonwoven sheet for the colorimetric film sensor. And color change of coated dye according to contact various gas samples (as strong acid and base, chloroform , ammonia and HF) of this dye-coated nonwoven film was examined for the application of chemically toxic materials detecting tools in the actual site of working place without aid of any kinds of detecting devices. By the addition of electron transfer agent (quinone derivati​​ves) , Continue reading

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