Using a Wavelet-Based and Fine-Tuned Convolutional Neural Network for Classification of Breast Density in Mammographic Images

Authors: Eri Matsuyama, Megumi Takehara, Du-Yih Tsai

ABSTRACT
Classification of breast density is significantly important during the process of breast diagnosis. The purpose of this study was to develop a useful computer-ized tool to help radiologists determine the patient’s breast density category on the mammogram. In this article, we presented a model for automatically classi-fying breast densities by employing a wavelet transform-based and fine-tuned convolutional neural network (CNN). We modified a pre-trained AlexNet model by removing the last two fully connected (FC) layers and appending two newly created layers to the remaining structure. Unlike the common CNN-based methods that use original or pre-processed images as inputs, we adopted the use of redundant wavelet coefficients at level 1 as inputs to the CNN model. Our study mainly focused on discriminating between scattered density and heterogeneously dense which are the two most difficult density cat-egories to differentiate for radiologists. The proposed system achieved 88.3% overall accuracy. In order to demonstrate the effectiveness and usefulness of the proposed method, the results obtained from a conventional fine-tuning CNN model was compared with that from the proposed method. The results demon-strate that the proposed technique is very promising to help radiologists and serve as a second eye for them to classify breast density categories in breast cancer screening.

Source:

Journal: Open Journal of Medical Imaging
DOI: 10.4236/ojmi.2020.101002(PDF)
Paper Id: 97911 (metadata)

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